INTRODUCTION Years after the AICPA wrote the audit guide on analytical procedures (APs) to improve the effectiveness of APs in practice (AICPA 1998), regulators continue to express concerns about auditors’ improper and deficient applications of substantive APs (PCAOB 2004; POB 2000). Glover, Prawitt, and Wilks (2005) (hereafter, GPW), not only contribute to a long line of research that addresses auditors’ effectiveness in applying APs, but also notably add to the sparsely researched area on APs used as substantive tests. This line of research is relevant for practice because, with increasing frequency, auditors are using substantive APs (Ameen and Strawser 1994; Asare and Wright 2001), yet APs used inappropriately have contributed to several accounting debacles including, in part, the WorldCom fraud (see Hitzig 2004). In this paper, GPW specifically address one reason why substantive APs may be ineffective (i.e., auditors’ improper assessment of AP design strength) and examine a possible cause (i.e., auditors’ sensitivity to outcome). The sensitivity to outcome is consistent with research related to the influence on auditors’ judgments of prior-year book values (e.g., McDaniel and Kinney 1995) and outcomes in planning AP (Lin et al. 2000), but heretofore has not been documented in a substantive AP application. In addition, because the assessment of AP strength (i.e., precision) is central to effective application and interpretation of APs, this research addresses a relevant practice issue and provides incremental evidence needed to address regulators’ calls for ways to improve auditors’ use of substantive APs. GPW ask whether a ‘‘favorable’’ outcome from a substantive AP (i.e., when the difference between the expected and book values is not significant) influences the extent to which auditors believe they can rely on the procedure. GPW predict that auditors seeing a favorable (i.e., no difference) outcome will over-rely on a weak procedure (i.e., one in which the auditor’s expectation is developed from relatively aggregated data). They also ask a second question: Will the requirement to evaluate the strength of the AP prior to evaluating its outcome reduce auditors’ over-reliance on weak APs?